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In Metal Gear Solid, Gray Fox appears under the identity of the Cyborg Ninja , an assassin in a powered exoskeleton and armed with a high-frequency blade, who challenges Solid Snake to a fist fight. He also provides Snake cryptic advice via CODEC as a faceless contact named Deepthroat. Gray Fox is later killed by Liquid Snake, piloting Metal Gear REX, after Fox destroys the vehicle's radome with the use of a laser cannon.
Despite Gray Fox's death in Metal Gear Solid, the Cyborg Ninja incarnation of the character would still appear in subsequent games in some form or another.