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Two years prior to the events of Galuade Incident, Viper and the rest of Black Chamber successfully recovered a prototype Metal Gear that had been hijacked by terrorists in South America, but upon returning were ambushed by FOXHOUND under orders from Roy Campbell. In the struggle, Viper lost his left arm and sustained internal injuries which should have killed him, though his hatred allowed him to survive and he swore to avenge his fallen comrades using Metal Gear GANDER.
During the Galuade Incident, he first encounters Snake after kidnapping Chris Jenner, and the two do battle in a room filled with tripwire explosives, the configuration of which Viper constantly alters. After Metal Gear GANDER is destroyed, Viper reveals that its true destructive capacity is its satellite uplink to nuclear-equipped attack satellites, and Snake is again forced to do battle with him aboard an elevator, to prevent Viper from activating the uplink upon reaching the surface. In both fights, Viper makes use of his prosthetic left arm, which is outfitted with a number of tricks, allowing him to blind his opponents with a flash light and emit shockwaves through his punches, among other abilities.
Viper is ultimately unsuccessful, and dies expressing regret for his inability to get revenge for the slain members of Black Chamber.