Laughing Octopus was the stealth expert of the Beauty and the Beast Unit. She, along with the other members, suffered from Post Traumatic Stress Disorder.
Laughing Octopus was first seen in the Middle East, along with the rest of the Beauty and the Beast Unit, attacking local rebels. She displayed her impressive camouflage abilities by hiding in the shadows before striking with her deadly tentacles, killing several soldiers before being called away by Screaming Mantis.
She later was stationed in South America, leading the French PMC, Pieuvre Armement, to attack the South American rebel forces. Arriving at Liquid's safe house, she and Vamp secure the area and capture several rebels and government forces. She kills all of the rebels except for one, at Vamp's request. Changing her face to match that of Snake's, she tells the survivor that Snake was the one that killed all of his comrades, which would cause the local regime to hunt him down. Using her tentacles to grab the armored van, she left with Vamp.
Laughing Octopus was then stationed at the research lab where Naomi Hunter was being held. Snake eventually reached the lab and made contact with Naomi, but she was quickly escorted off of the premises by Pieuvre Armement troops and the lab was rushed by FROGS, commanded by Octopus. After Snake eliminated the FROGS, Octopus entered the lab herself, formally introducing herself to Snake before attacking him.
Despite her impressive camouflaging and ambush techniques, Snake was able to defeat Octopus. Once defeated, her octopus helmet and face mask fell off, and Octopus fell to the ground.
